By Stephen C. DeVito, Roger L. Garrett
content material: pollutants prevention, eco-friendly chemistry, and the layout of more secure chemical compounds / Roger L. Garrett --
common ideas for the layout of more secure chemical substances : toxicological concerns for chemists / Stephen C. DeVito --
melanoma danger aid via mechanism-based molecular layout of chemical substances / David Y. Lai ... [et al.] --
Isosteric substitute of carbon with silicon within the layout of more secure chemical compounds / Scott McN. Sieburth --
layout of biologically more secure chemical compounds in response to retrometabolic ideas / Nicholas Bodor --
Predicting charges of cytochrome-P450-mediated bioactivation and its software to the layout of more secure chemical compounds / Jeffrey P. Jones --
Use of desktops in toxicology and chemical layout / G.W.A. Milne, S. Wang, and V. Fung --
Designing biodegradable chemical substances / R.S. Boethling --
Designing aquatically more secure chemical substances / Larry D. Newsome, J. Vincent Nabholz, and Anne Kim --
Designing more secure nitriles / Stephen C. DeVito --
Designing an environmentally secure marine antifoulant / G.L. Willingham and A.H. Jacobson --
Imine-isocyanate chemistry : new know-how for environmentally pleasant, high-solids coatings / Douglas A. Wicks and Philip E. Yeske.
Read or Download Designing Safer Chemicals. Green Chemistry for Pollution Prevention PDF
Similar pollution books
The auto is without doubt one of the innovations that has made a decisive contribution to human mobility, and accordingly it has turn into an inseparable a part of sleek human society. although, it really is via this frequent use that its adverse affects at the setting became so hugely seen. Achievements in enhancing the ecological features of the car are hugely striking: a latest vehicle emits just a fraction of the quantities of noise and exhaust toxins produced through its predecessors 30 years in the past.
Because the mid Nineteen Nineties, criminal motion to get rid of power natural toxins (POPs) has all started leading to an international conference on POPs, the Stockholm conference, and a nearby Protocol lower than the conference on Long-Range Transboundary pollution (UN-ECE LRTAP Convention). POPs are characterised via lengthy half-lives, patience within the atmosphere, they suffer long-range delivery, collect within the setting and in biota, and they're poisonous.
Commercial and agricultural job all through this century has resulted in significant infection of soil and groundwater assets by means of unsafe chemical compounds. The means of bioremediation makes use of residing organisms--usually micro organism and fungi--to eliminate pollution from soil and water with minimum disturbance to those environments.
International warming has worsened the water source concern in lots of arid zones around the globe, from Africa to Asia, affecting thousands of individuals and placing them liable to starvation. potent administration of arid region assets, together with figuring out the dangers of poisonous hint and heavy components to people, coupled with the necessity to produce extra nutrition to feed the world’s transforming into inhabitants, has therefore turn into more and more vital.
- Pollution in China
- Pollution Engineering March 2011
- Handbook of Chemical Technology and Pollution Control
- Constructed Wetlands in Water Pollution Control. Proceedings of the International Conference on the Use of Constructed Wetlands in Water Pollution Control, Held in Cambridge, UK, 24–28 September 1990
- Indoor Environment - Airborne Particles and Settled Dust
- Pollution prevention and abatement handbook, 1998: toward cleaner production, Page 777
Extra info for Designing Safer Chemicals. Green Chemistry for Pollution Prevention
From such information the environmentally conscious chemist can often design a new substance such that it will be both safe and commercially useful. The remainder of this section provides specific examples of the design of safer analogs of important commercial chemical substances whose toxic effects and mechanisms are well known but not apparentfromtheir structures. The chapters entitled Cancer Risk Reduction Through Mechanism-Based Molecular Design of Chemicals (by Lai, et al) and Designing Safer Nitriles (by DeVito) provide more detailed examples on how an understanding of toxic mechanisms can be used to design safer commercial chemical substances.
The sulfate moiety of 10 is a particularly good leaving group because the resulting carbocation (11) is both benzylic and allylic and, thus, highly resonance stablized. 1). When designing alcohols, chemists should avoid placing C=C moieties on any carbon atom that contains both the -OH group and at least one hydrogen atom, as such allyl alcohols are likely to undergo enzymatic oxidation to a,6-unsaturated carbonyl metabolites. Chemists should also avoid placing an aromatic substituent onto the alcoholic carbon of allyl alcohols.
Teratogenicity (also known as developmental toxicity) is the ability of a substance to cause a toxic effect in the fetus or offspring, following maternal administration of the substance anytime prior to or during gestation. These toxic effects can vary widely, andfrequentlyinclude: structural abnormalities; altered growth; mental retardation; blindness; deafness; cleft palate; functional deficits; and death. The teratogenic effects of carboxylic acids include skeletal defects (extra presacral vertebrae, fused ribs), exencephaly, reduced fetal weight, neural tube defects, and death (74).
Designing Safer Chemicals. Green Chemistry for Pollution Prevention by Stephen C. DeVito, Roger L. Garrett